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KMID : 0882420060700030342
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Korean Journal of Medicine
2006 Volume.70 No. 3 p.342 ~ p.346
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A case of fulminant type 1 diabetes mellitus
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이상열/Rhee SY
전숙/고관표/오승준/우정택/김진우/김영설/Chon S/Koh GP/Oh SJ/Woo JT/Kim JW/Kim YS
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Abstract
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A novel subtype of type 1B diabetes with rapid onset and no evidence of autoimmunity has been recently proposed as fulminant type 1 diabetes. The pathogenesis of fulminant type 1 diabetes has not been fully understood. We report a case of fulminant type 1 diabetes with diabetic ketoacidosis. A 31-year-old male was referred to our hospital because of high plasma glucose level and acidosis. Laboratory findings were rendering a diagnostic picture of diabetic ketoacidosis with acute renal insufficiency. While there was high plasma glucose, normal HbA1c and other laboratory findings suggested a very recent onset of diabetes mellitus. A test to detect antibodies to islet cell antigen IA-2 was negative, but those of glutamic acid decarboxylase (GAD) was weakly positive. The patient successfully recovered without any serious complication after fluid and insulin based management.
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KEYWORD
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